MR elastography of the liver at 3 T with cine-tagging and bending energy analysis: preliminary results

作者：Watanabe Haruo^*; Kanematsu Masayuki; Kitagawa Teruhiko; Suzuki Yuriko; Kondo Hiroshi; Goshima Satoshi; Kajita Kimihiro; Bae Kyongtae T; Hirose Yoshinobu; Miotani Seiki; Zhou Xiangrong; Fujita Hiroshi

来源：European Radiology, 2010, 20(10): 2381-2389.

DOI：10.1007/s00330-010-1800-0

• MR imaging
• Liver fibrosis
• 3 Tesla
• Elastography
• Cine-tagging

To preliminarily evaluate the feasibility and usefulness of MR elastography of the liver at 3 T with cine-tagging and bending energy (BE) analysis for the evaluation of hepatic fibrosis.
Twenty-two patients underwent MR elastography with four different cine-tagging grids on the liver (16- or 20-mm sagittal or coronal). Nine images serially obtained during 1-s of exhalation were analyzed to define coordinates of grid intersections. BE values were calculated using the thin-plate spline method. BE values were compared among patient groups with different fibrosis stage thresholds.
In the 22 patients, six had a fibrosis score of F0, one had F1, seven had F2, three had F3, and five had F4. Mean BE value with 16-mm sagittal grid was greater with fibrosis score F0 (1.54 +/- 0.63) than with a parts per thousand yenF1 (0.97 +/- 0.12, P = 0.013) as well as with a parts per thousand currency signF1 (1.48 +/- 0.60) than with a parts per thousand yenF2 (0.96 +/- 0.36, P = 0.019).
Our results showed that MR elastography with 16-mm sagittal grid and BE analysis had a potential in discrimination for the patients with moderate or advanced hepatic fibrosis from those with healthy liver or slight fibrosis.

• 出版日期2010-10