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摘要
An efficient and convenient palladium-catalyzed cyclization reaction of alkynes with isocyanides is described herein. This protocol allows the practical synthesis of many valuable polysubstituted maleimide derivatives after hydrolysis with a broad scope of substrates and mild reaction conditions. C-C, C=O, and C-N bonds were constructed in this transformation with isocyanide serving as both C and N sources.
- 出版日期2016-12-16
- 单位华南理工大学
