摘要

With the ever growing concerns of new HIV infections around the world, despite the best possible comprehensive resource mobilization, it is desired to develop microbicides for vaginal and anal applications to prevent the transmission of HIV virus especially among the most vulnerable women usually devoid of their sexual and reproductive rights. Researches need to focus on the costing, availability, accessibility, applicability, efficiency and effectiveness of the microbicides to be used across strata of extremely different socio cultural dimensions, individual practices, preferences and habits. Therefore, the challenges continue to be addressed with initial reports and history of observed failures. The golden edge visible for success of various other microbicides shows the path of success towards reaching a consensus for scientifically. developed rnicrobicides and their use after all the phases of trials are over. However, queries related to the highly potent drugs and their limited usefulness need to be resolved by the careful and cautious application of mind by the drug control authorities and related drug distribution systems across nations. The overall and comparative assessment of the drugs being tested as microbicides along with the experiences gained in the field will clarify; the scenario for further subsequent actions at the levels of policy makers, implementers and interventionists.