Differential phase-contrast interior tomography

作者：Cong Wenxiang^*; Yang Jiangsheng; Wang Ge

来源：Physics in Medicine and Biology, 2012, 57(10): 2905-2914.

DOI：10.1088/0031-9155/57/10/2905

Differential phase-contrast interior tomography allows reconstruction of a refractive index distribution over a region of interest (ROI) for visualization and analysis of structures inside a large biological specimen. In the imaging mode, x-ray scanning only targets an ROI in an object and a narrow beam passes through the object, allowing a significant reduction of both radiation dose and system cost. Inspired by recently developed compressive sensing theory, in a numerical analysis framework we show that accurate interior reconstruction can be achieved on an ROI from truncated differential projection data through the ROI via the total variation minimization, assuming a piecewise constant distribution of the refractive indices in the ROI. Then, we develop a practical iterative algorithm for such an interior reconstruction and perform numerical experiments to demonstrate the feasibility of the proposed approach.

• 出版日期2012-5-21
• 单位Virginia Tech; 北京大学; 美国弗吉尼亚理工大学(Virginia Tech)