Applications of calixarenes in cancer chemotherapy: facts and perspectives

作者:Yousaf Ali; Abd Hamid Shafida*; Bunnori Noraslinda M; Ishola A A
来源:Drug Design, Development and Therapy, 2015, 9: 2831-2838.
DOI:10.2147/DDDT.S83213

摘要

Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. The anticancer activity of various functionalized calixarenes has been reported by several research groups. Due to their superior geometric shape, calixarenes can accommodate drug molecules by forming inclusion complexes. Controlled release of anticancer drugs by calixarenes might help in targeted chemotherapy. This review summarizes the anticancer potential of the calixarenes and their drug loading properties. The potential use of calixarenes in chemoradiotherapy is also highlighted in brief.

  • 出版日期2015