Accumulated exposure to rural areas of residence over the life course is associated with overweight and obesity in adulthood: a 25-year prospective cohort study

作者：Patterson Kira A E; Gall Seana L; Venn Alison J; Otahal Petr; Blizzard Leigh; Dwyer Terry; Cleland Verity J^*

来源：Annals of Epidemiology, 2017, 27(3): 169-175.

DOI：10.1016/j.annepidem.2017.01.007

• Obesity
• Rural health
• Longitudinal studies
• Life course
• Body mass index
• Body weight

Purpose: This prospective cohort study investigated whether body mass index (BMI) and weight status in mid -adulthood were predicted by trajectories of urban -rural residence from childhood to adulthood.
Methods: Participants aged 7-15 years in 1985 (n = 8498) were followed up in 2004-2006 (n = 3999, aged 26-36 years) and 2009-2011 (n = 3049, aged 31-41 years). Area of residence (AOR) was classified as urban or rural at each time point. BMI and/or weight status was calculated from self-reported weight and height (2009-2011). We tested which of three life-course models ("accumulation," "sensitive period," "mobility") best explained the AOR-BMI and/or weight status association using a novel life-course modeling framework.
Results: Accumulation and sensitive period models best described the effect of AOR on mid-adulthood BMI and weight status. Those with greater accumulated exposure to rural areas had a higher BMI ((beta = 0.29 kg/m(2) per time in a rural area, P =.005) and were more likely obese (relative risk =1.13 per time in a rural area, P =.002). Living in rural areas at ages 26-30 years was also associated with a higher BMI and obesity in mid-adulthood.
Conclusions: Greater cumulative exposure to rurality and exposure during the "sensitive period" of young adulthood is associated with obesity in middle-aged adults. This study highlights the important contribution of context to the development of obesity over the life course.

• 出版日期2017-3
• 单位河北医科大学