Hybrid Spectral Micro-CT: System Design, Implementation, and Preliminary Results

作者：Bennett James R; Opie Alex M T; Xu Qiong; Yu Hengyong; Walsh Michael; Butler Anthony; Butler Phillip; Cao Guohua; Mohs Aaron; Wang Ge^*

来源：IEEE Transactions on Biomedical Engineering, 2014, 61(2): 246-253.

DOI：10.1109/TBME.2013.2279673

• CT architecture
• CT instrumentation
• interior tomography
• micro-CT
• spectral-CT

Spectral CT has proven an important development in biomedical imaging, and there have been several publications in the past years demonstrating its merits in pre-clinical and clinical applications. In 2012, Xu et al. reported that near-term implementation of spectral micro-CT could be enhanced by a hybrid architecture: a narrow-beam spectral %26quot;interior%26quot; imaging chain integrated with a traditional wide-beam %26quot;global%26quot; imaging chain. This hybrid integration coupled with compressive sensing (CS)-based interior tomography demonstrated promising results for improved contrast resolution, and decreased system cost and radiation dose. The motivation for the current study is implementation and evaluation of the hybrid architecture with a first-of-its-kind hybrid spectral micro-CT system. Preliminary results confirm improvements in both contrast and spatial resolution. This technology is shown to merit further investigation and potential application in future spectral CT scanner design.

• 出版日期2014-2
• 单位美国弗吉尼亚理工大学(Virginia Tech); 西安交通大学