A catalytic crossed-aldol condensation of ketones with aromatic and non-aromatic aldehydes by silica supported Preyssler heteropOlyacids catalyst

作者：Gharib Ali^*; Pesyan Nader Noorozi; Jahangir Manouchehr; Roshani Mina; Scheeren J W

来源：Bulgarian Chemical Communications, 2013, 45(3): 314-325.

• alpha,beta-unsaturated aldol
• catalysts
• aldehyde
• ketone
• condensation

Synthesis of alpha,beta-unsaturated aldol products by crossed-aldol condensation of aromatic aldehydes in the presence of heteropolyacids (HPAs) catalyst under reflux conditions and free of organic solvent is reported. Aldol condensation of 2-acetylthiophene, 2-acetylpyrrole and 2-acetylpyridine with different aromatic aldehydes was carried out in water in the presence of a silica supported Preyssler HPAs catalyst at room temperature.. All reactions occur in a short time with excellent yields of cycloalkanones in water as an environmentally friendly solvent.

• 出版日期2013