The clinical research for Ganoderan's effect on preventing and treating cerebral arteriosclerosis through inhibiting NADPH oxidizing enzyme expression

作者：Feng Zhang Li; Fang Teng Jun^*; Qian Yuan Xue; Rong Wang Huan

来源：Pakistan Journal of Pharmaceutical Sciences, 2014, 27(4): 1107-1111.

• Ganoderan
• NADPH oxidizing enzyme
• arteriosclerosis

A lot of researches have verified that produced excessive reactive oxygen is one of the hazard factors causing atherosclerosis. NADPH oxidase is the main protease of vascular cell's producing reactive oxygen, the expression of its relevant subunits is closely correlated with the occurring and development process of atherosclerosis. Oxidizing reaction could damage organism tissue cells, ganoderan has very significant effect on the anti-oxidizing function of cell. The pharmaceutical research of ganoderan has significant meaning in curing diabetes mellitus, preventing and controlling arteriosclerosis. This paper is mainly to discuss the effect of anoderan's inhibiting NADPH oxidizing enzyme expression on preventing and treating cerebral arteriosclerosis and its action mechanism.

• 出版日期2014-7
• 单位郑州大学