A neural mass model of cross frequency coupling

作者:Chehelcheraghi Mojtaba; van Leeuwen Cees; Steur Erik; Nakatani Chie
来源:PLos One, 2017, 12(4): e0173776.
DOI:10.1371/journal.pone.0173776

摘要

Electrophysiological signals of cortical activity show a range of possible frequency and amplitude modulations, both within and across regions, collectively known as cross-frequency coupling. To investigate whether these modulations could be considered as manifestations of the same underlying mechanism, we developed a neural mass model. The model provides five out of the theoretically proposed six different coupling types. Within model components, slow and fast activity engage in phase-frequency coupling in conditions of low ambient noise level and with high noise level engage in phase-amplitude coupling. Between model components, these couplings can be coordinated via slow activity, giving rise to more complex modulations. The model, thus, provides a coherent account of cross-frequency coupling, both within and between components, with which regional and crossregional frequency and amplitude modulations could be addressed.

  • 出版日期2017-4-5