A facile access to substituted indoles utilizing palladium catalyzed annulation under microwave enhanced conditions

作者：Karuvalam Ranjith P; Haridas Karickal R^*; Sajith Ayyiliath M; Muralidharan Arayambath

来源：Tetrahedron Letters, 2013, 54(37): 5126-5129.

DOI：10.1016/j.tetlet.2013.07.073

• Indole
• PdCl2
• A-taphos
• Microwave

A facile access to differently substituted indoles using palladium catalyzed annulation reactions under microwave enhanced conditions has been achieved. A highly active and efficient catalytic system PdCl2/(A-taphos) for the synthesis of indole via palladium catalyzed ring annulation of ortho iodo anilines and aldehydes has been developed.

• 出版日期2013-9-11