A high-performance magnetic resonance imaging T-2 contrast agent

作者:Qin Jian; Laurent Sophie; Jo Yun Suk; Roch Alain; Mikhaylova Maria; Bhujwalla Zaver M; Muller Robert N; Muhammed Mamoun*
来源:Advanced Materials, 2007, 19(14): 1874-+.
DOI:10.1002/adma.200602326

摘要

A high-performance magnetic resonance imaging T-2 contrast agent has been prepared via phase transfer of hydrophobic superparamagnetic iron oxide nanoparticles (SPIONs) to an aqueous solution by using Pluronic F127 copolymers. As seen in the figure, a hierarchical structure of the surface coating is formed and proven to be a crucial characteristic to enhance not only water dispersibility, but also the efficacy as a T-2 contrast agent.

  • 出版日期2007-7-16