Anthraquinon-2-ylethyl-1 ';,2 ';-diol (Aqe-diol) as a new photolabile protecting group for aldehydes and ketones

作者：Yu Jing yu; Tang Wen Jian; Wang Hong Bo; Song Qin Hua^*

来源：Journal of Photochemistry and Photobiology A: Chemistry , 2007, 185(1): 101-105.

DOI：10.1016/j.jphotochem.2006.05.010

• photolabile protecting groups
• 2-(1,2-dihydroxyethyl) anthraquinone
• aldehydes and ketones
• photochemistry

A new photolabile protecting group for aldehydes and ketones, 2-(1,2-dihydroxyethyl) anthraquinone (Aqe-diol) and four caged compounds have been prepared and their photochemistry investigated. Upon 350 nm light irradiation, the caged compounds 2a-d in CH3CN-H2O solution can efficiently release the carbonyl compounds (conversion rate 60-90%), and their uncaging quantum efficiencies were measured, ranging from 0.03 to 0.09. On the basis of HPLC analysis and quenching experiments, a mechanism of the uncaging reaction was suggested.

• 出版日期2007-1-1
• 单位中国科学技术大学