摘要
A copper-catalyzed cascade dehydrogenative and dehalogenative reaction of halogenated 6-phenyl-4,5-dihydropyridazin-3(2H)-ones to 6-phenylpyridazin-3(2H)-ones has been developed. Moreover, the catalytic system consisting of copper(II) acetate/sodium carbonate/pyridine exhibits high reactivity and selectivity with oxygen as the terminal oxidant.
- 出版日期2013-5
- 单位北京大学; 天然药物与仿生药物国家重点实验室