An enantioselective cascade reaction between alpha, beta-unsaturated aldehydes and malonic half-thioesters: a rapid access to chiral delta-lactones

作者:Ren Qiao; Sun Shaofa*; Huang Jiayao; Li Wenjun; Wu Minghu; Guo Haibing; Wang Jian
来源:Chemical Communications, 2014, 50(46): 6137-6140.
DOI:10.1039/c4cc01736f

摘要

We disclose a novel efficient enantioselective organocatalytic cascade reaction for the preparation of delta-lactones in good to excellent yields (69-93%) and with high to excellent enantioselectivities (88-96% ee).