Dietary polyphenols, oxidative stress and antioxidant and anti-inflammatory effects

作者：Zhang, Hua; Tsao, Rong^*

来源：Current Opinion in Food Science, 2016, 8: 33-42.

DOI：10.1016/j.cofs.2016.02.002

• ARYL-HYDROCARBON RECEPTOR
• NLRP3 INFLAMMASOME ACTIVATION
• DRUG-METABOLIZING-ENZYMES
• MEDIATED INFLAMMATION
• QUERCETIN
• AHR
• RESVERATROL
• MECHANISMS
• EXPRESSION
• GREEN

Phenolic compounds including phenolic acids, flavonoids and proanthocyanidins are widely distributed in plants as a protective mechanism against biotic and abiotic stresses. Fruits, vegetables, grains, spices and herbs are the richest source of dietary polyphenols. High intake of these foods has been linked to lowered risk of most common degenerative and chronic diseases that are known to be caused by oxidative stress. This review intends to summarize briefly recent progress on the chemistry and biochemistry of dietary polyphenols, their antioxidant and anti-inflammatory activities, and the underlying molecular mechanisms of their involvement in inflammation mediated metabolic diseases are also discussed. Perspectives for future research are also briefly discussed.

• 出版日期2016-4