No evidence for a role of xenotropic murine leukaemia virus-related virus and BK virus in prostate cancer of German patients

作者：Akguel Baki; Pfister David; Knuechel Ruth; Heidenreich Axel; Wieland Ulrike; Pfister Herbert^*

来源：Medical Microbiology and Immunology, 2012, 201(2): 245-248.

DOI：10.1007/s00430-011-0215-0

• Prostate cancer
• Viral infection
• BKPyV
• XMRV

Prostate cancer is one of the most prevalent types of cancer in men. Controversial data exist concerning the role of BKPyV and the xenotropic murine leukaemia virus-related gammaretrovirus (XMRV) in prostate cancer development. We therefore assessed the association between prostate cancer and viral infections. We could detect BKPyV in only 1 out of 85 prostate cancer samples, whereas none of the tissue samples showed evidence for XMRV positivity. Lack of detection of BKPyV and XMRV in prostate cancer tissues suggests that these viruses do not play a role in the pathogenesis of this type of cancer.

• 出版日期2012-5