A new entry to the phenanthridine ring system

作者：Mondal Poulomi; Thander Latibuddin; Chattopadhyay Shital K^*

来源：Tetrahedron Letters, 2012, 53(11): 1328-1331.

DOI：10.1016/j.tetlet.2011.12.095

• aza-Claisen rearrangement
• Catalysis
• Ring-closing enyne metathesis
• Diels-Alder reaction
• Isomerisation
• Phenanthridine
• Heterocycle

A new synthesis of phenanthridine derivatives having three-point diversity has been developed based on the sequential application of three-atom economic processes viz. aza-Claisen rearrangement, ring-closing enyne metathesis and Diels-Alder reaction as key steps. An unexpected isomerisation was observed during aza-Claisen rearrangement of N-allylanilines which may open up new opportunities in heterocyclic synthesis.

• 出版日期2012-3-14