Multiwalled carbon nanotube-4-tert-butyl calix[6]arene composite electrochemical sensor for clenbuterol hydrochloride determination by means of differential pulse adsorptive stripping voltammetry

作者：Gaichore Reena R; Srivastava Ashwini K^*

来源：Journal of Applied Electrochemistry, 2012, 42(11): 979-987.

DOI：10.1007/s10800-012-0466-5

• Electrochemical sensor
• Clenbuterol hydrochloride
• Voltammetry
• Biological fluids

The electrochemical behavior of clenbuterol hydrochloride (CLB) was studied at a multiwalled carbon nanotube-4-tert-butyl calix[6]arene composite chemically modified electrode by means of cyclic voltammetry, electron impedance spectroscopy, and differential pulse adsorptive stripping voltammetry. Surface characterization of the electrode was carried out by means of SEM. The results revealed that 4-tert-butyl calix[6]arene along with multiwalled carbon nanotubes demonstrated a high sensitivity for determination of CLB. Employing differential pulse adsorptive stripping voltammetry allowed a linear response over the concentration range of 1.99 x 10(-8)-4.76 x 10(-5) M with a detection limit of 1.38 x 10(-9) M for CLB. The described method has been applied for the estimation of CLB in biological fluids such as urine and serum.

• 出版日期2012-11