A case of acetaminophen (paracetamol) causing renal failure without liver damage in a child and review of literature

作者：Ozkaya Ozan; Genc Gurkan^*; Bek Kenan; Sullu Yurdanur

来源：Renal Failure, 2010, 32(9): 1125-1127.

DOI：10.3109/0886022X.2010.509830

• children
• acetaminophen
• renal failure
• pathophysiology
• nephrotoxicity

Acetaminophen (paracetamol) is a widely used drug and known as a safety antipyretic and analgesic drug in childhood. Acetaminophen-associated liver damage is more recognized than kidney damage. Nephrotoxicity and hepatotoxicity can be seen together after acetaminophen overdose, but renal damage without liver damage is a rarely seen entity in all age groups being reported more rarely in childhood. We present here a 16-year-old girl with renal failure without liver damage because of acetaminophen toxicity and a review of literature for pathophysiological mechanisms, clinical course, treatment, and outcome.

• 出版日期2010