An efficient intermolecular C(aryl)-S bond forming reaction catalyzed by BINAM-copper(II) complex

作者：Prasad D J C; Naidu Ajay B; Sekar G^*

来源：Tetrahedron Letters, 2009, 50(13): 1411-1415.

DOI：10.1016/j.tetlet.2009.01.022

• Ullmann coupling
• C-S bond formation
• Copper catalyst
• Diamine ligand
• Thioethers

A wide range of diaryl thioethers and aryl alkyl thioethers; are synthesized from the corresponding aryl iodides and aromatic/aliphatic thiols through Ullmann type intermolecular coupling reactions in the presence of a catalytic amount of easily available BINAM-Cu(OTf)(2) complex. Less reactive aryl bromides have also been shown to react with thiols under identical reaction conditions to give good yields of the thioethers without increasing the reaction temperature and time.

• 出版日期2009-4-1