Highly diastereoselective synthesis of tetrahydrobenzofuranones by palladium-catalyzed reaction of propargylic carbonates with 2-substituted cyclohexane-1,3-diones

作者：Yoshida Masahiro^*; Higuchi Mariko; Shishido Kozo

来源：Tetrahedron Letters, 2008, 49(10): 1678-1681.

DOI：10.1016/j.tetlet.2007.12.123

The reaction of propargylic carbonates with 2-substituted cyclohexane-1,3-diones in the presence of palladium catalyst is described. Substituted tetrahydrobenzofuranones having a quaternary carbon stereocenter were synthesized in a highly diastereoselective manner.

• 出版日期2008-3-3