Ultrasounds in Melted Poly( ethylene glycol) Promote Copper- Catalyzed Cyanation of Aryl Halides with K-4[ Fe( CN)(6)]

作者：Giachi Guido^*; Frediani Marco; Oberhauser Werner; Lamaty Frederic; Martinez Jean; Colacino Evelina

来源：Chemsuschem, 2014, 7(3): 919-924.

DOI：10.1002/cssc.201300997

• catalysis
• copper
• cyanation
• poly(ethylene glycol)
• sonochemistry

Melted poly(ethylene glycols) (PEGs) were used for the first time as solvent for the sonochemically promoted cyanation of aryl halides employing inexpensive and safe K-4[Fe(CN)(6)] and a relatively low amount of Cu-based catalyst. The M-w (weight-average polymer molecular weight) of PEG proved to notably influence the substrate conversion, which is indicative of a strong dependence of the sonication efficacy on solvent properties. Gel permeation chromatography (GPC), X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM) contributed to the characterization of the polymer and the elucidation of the catalytic system.

• 出版日期2014-3