Ammonium salt catalyzed multicomponent transformation: simple route to functionalized spirochromenes and spiroacridines

作者：Dabiri Minoo^*; Bahramnejad Mahboobeh; Baghbanzadeh Mostafa

来源：Tetrahedron, 2009, 65(45): 9443-9447.

DOI：10.1016/j.tet.2009.08.070

• Multicomponent transformation
• Spirooxindoles
• Ammonium chloride
• Water
• Heterocycle

The combination of isatin or acenaphthoquinone, an activated methylene reagent, and 1,3-dicarbonyl compounds in the presence of catalytic ammonium chloride was found to be a suitable and efficient method for the synthesis of the biologically important spirooxindoles.

• 出版日期2009-11-7