Asymmetric Henry reaction catalyzed by a Zn-amino alcohol system

作者：Zheng, Bing; Wang, Min; Li, Zhiyuan; Bian, Qinghua; Mao, Jianyou; Li, Shuoning; Liu, Shangzhong; Wang, Mingan; Zhong, Jiangchun^*; Guo, Hongchao

来源：Tetrahedron: Asymmetry , 2011, 22(11): 1156-1160.

DOI：10.1016/j.tetasy.2011.06.032

• SALEN-CHROMIUM COMPLEXES
• NITROALDOL REACTION
• DIETHYLZINC ADDITION
• ALDEHYDES
• LIGANDS
• EFFICIENT
• DESIGN

The enantioselective Henry reaction between nitromethane and various aldehydes catalyzed by chiral amino alcohol-Zn complex was described. The resulting beta-nitroalcohols were obtained in high yields and with moderate to good enantiomeric excesses.

• 出版日期2011-6-15
• 单位中国农业大学