Affective prosody perception in symptomatically remitted patients with schizophrenia and bipolar disorder

作者：Hoertnagl Christine M; Yalcin Siedentopf Nursen; Baumgartner Susanne; Biedermann Falko; Deisenhammer Eberhard A; Hausmann Armand; Kaufmann Alexandra; Kemmler Georg; Muehlbacher Moritz; Rauch Anna Sophia; Fleischhacker Wolfgang W; Hofer Alex^*

来源：Schizophrenia Research, 2014, 158(1-3): 100-104.

DOI：10.1016/j.schres.2014.07.019

• Schizophrenia
• Bipolar disorder
• Affective prosody perception
• Social cognition

Affect perception has frequently been shown to be impaired in patients suffering from schizophrenia or bipolar disorder (BD), but it remains unclear whether these impairments exist during symptomatic remission and whether the two disorders differ from each other in this regard. Most previous studies have investigated facial affect recognition, but not the ability to decode mental states from emotional tone of voice, i.e. affective prosody perception (APP). Accordingly, the present study directly compared APP in symptomatically remitted patients with schizophrenia or BD and healthy control subjects and investigated its relationship with residual symptomatology in patients. %26lt;br%26gt;Patients with schizophrenia and BD showed comparable APP impairments despite being symptomatically remitted. In comparison to healthy control subjects, overall APP deficits were found in BD but not in schizophrenia patients. Both patient groups were particularly impaired in the identification of anger and confounded it with neutral prosody. In addition, schizophrenia patients frequently confused sadness with happiness, anger, or fright. There was an inverse association between the degree of residual positive symptoms and the ability to correctly recognize happiness in schizophrenia patients. %26lt;br%26gt;Overall, these data indicate that impairments in APP represent an enduring deficit and a trait marker of both schizophrenia and BD and that the level of impairment is comparable between disorders.

• 出版日期2014-9