Multiple atypical recurrent meningiomas 13 years after radiotherapy for unilateral retinoblastoma: case report and review of the literature

作者：Aras Yavuz; Akcakaya Mehmet Osman^*; Aydoseli Aydin; Meral Rasim; Kiris Talat

来源：Neurologia i Neurochirurgia Polska, 2013, 47(1): 80-85.

DOI：10.5114/ninp.2013.32932

• radiotherapy
• meningioma
• radiation-induced tumour
• secondary brain neoplasms in children
• retinoblastoma

Radiotherapy is an important treatment modality for intracranial malignancies. Improved survival rates were achieved via a combination of surgery, chemotherapy and radiotherapy. On the other hand, improved survival rates made long-term complications of radiotherapy more apparent. Secondary neoplasms due to cranial irradiation are encountered more commonly in neurosurgical practice. Radiation-induced meningiomas are recognized as a common late complication of radiotherapy. However, radiation-induced meningiomas after radiotherapy for retinoblastoma have been reported rarely. Herein we report a patient who harboured multiple meningiomas 13 years after radiotherapy for unilateral retinoblastoma, which were recurrent despite surgical removal and chemotherapy.

• 出版日期2013-2