Angelo Mosso's Experiments at Very Low Barometric Pressures

作者：Di Giulio Camillo; West John B^*

来源：High Altitude Medicine & Biology, 2013, 14(1): 78-79.

DOI：10.1089/ham.2012.1082

• Paul Bert
• hypoxia
• acapnia
• extreme altitude
• hypobaria

Di Giulio C, and West JB. Angelo Moss's experiments at very low barometric pressures. High Alt Med Biol 14:78-79, 2013.-In 1898, Angelo Mosso (1846-1910) used his low-pressure chambers to carry out some remarkable experiments that are not well known. Paul Bert (1833-1886) had previously demonstrated that the deleterious effects of high altitude were due to low P-O2, but this conclusion was disputed by many of the eminent scientists of the day. Mosso believed that the physiological effects of high altitude were caused by a low P-CO2 (acapnia) and he made a series of low-pressure chamber experiments to test this. In some studies he added oxygen to the air in the chambers so that he could study the effects of extreme hypobaria; in one experiment he survived a barometric pressure of only 192 mm Hg equivalent to an altitude of about 10,800 m. Some of his experiments were observed by his daughter Mimi who wrote a colorful account in her book dedicated to her father "Un cercatore d'ignoto'' (A seeker of the unknown).

• 出版日期2013-3