Analysis of dengue virus burden and serotypes pattern in Faisalabad, 2016-2017

作者：Yousaf Muhammad; Junaid Kashaf; Iqbal Muhammad Sarfaraz^*; Aslam Imran; Ahmad Sheraz; Aqeel Muhammad; Ashfaq Usman Ali; Khaliq Saba; Ghani Muhammad Usman; Waqar Nayyar

来源：Future Virology, 2018, 13(4): 245-251.

DOI：10.2217/fvl-2017-0155

• arboviral
• dengue
• dengue shock syndrome
• DSS
• Faisalabad
• Flaviviridae
• serotypes
• viral RNA

Dengue is the fastest growing mosquito-borne viral infection and has become a public epidemic in Pakistan. This cross-sectional study was carried out to explore the prevalence and characterization of dengue virus serotypes in Faisalabad, Pakistan during 2016-2017. Aim: To determine most prevalent dengue serotype in Faisalabad, Pakistan. Methodology: Cross-sectional study of stored serum specimens for dengue virus genotype by multiplex real time (RT)-PCR, antidengue IgM, IgG and NS1. Results: Viral RNA detection of 42 patients revealed positive results in 125 (34.4%) samples. DENV-3 (76%) was the predominant genotype followed by DENV-2 (17%) and 7% of DENV1. None of the samples were positive for DENV-4. Conclusion: DENV-3 is the most prevalent serotype of dengue virus observed in Faisalabad, Pakistan.

• 出版日期2018-4
• 单位河北医科大学