Detection of Faults and Barriers on Automated Large-Scale 2-D EWOD Digital Microfluidics

作者：Li, Chunqiao^*; Wang, Wei; Chao, Lei; Ji, Xiumin; Zhou, Jia

来源：Journal of Microelectromechanical Systems, 2017, 26(6): 1449-1456.

DOI：10.1109/JMEMS.2017.2764139

• Electro-wetting
• fault and barrier detection
• impedance detection
• large-scale digital microfluidics (DMF)

In lab on chip applications, on-chip detection of faults and barriers on electrowetting-on-dielectric (EWOD) digital microfluidics (DMFs) shows great significance for precise results. In this paper, we develop a sensor-free all-electronic integrated system based on one set of impedance detection circuits for all electrodes. Calibration, precise, and real-time droplet detection and result exhibition are realized through the operating electronic hardware and software. A specific voltage transforming method is proposed for fast detection. A significant practice of cyberphysical coupling in digital microfluidics is demonstrated through a 10 x 10 DMF. The detection sensitivity and consistency of the system shows the feasibility of the system. The 100% agreement between the experimental results and the real map of droplets on DMF demonstrates the capability of the system applicable for large-scale 2-D EWOD DMFs, and provides preliminary requirements for auto-routing. [2017-0164]

• 出版日期2017-12
• 单位复旦大学