Potential Mechanism for the Laser-Fluoride Effect on Enamel Demineralization

作者：Liu Y; Hsu C Y S^*; Teo C M J; Teoh S H

来源：Journal of Dental Research, 2013, 92(1): 71-75.

DOI：10.1177/0022034512466412

• low energy
• non-invasive
• microXRD
• micro-CT
• caries
• mineral loss

Laser-induced prevention of dental caries has been studied extensively. However, the cariostatic mechanisms of a combined fluoride-laser treatment are not well-understood. Using micro-computed tomography (micro-CT), we quantified the effect of fluoride and/or Er:YAG laser treatment on enamel demineralization. The mean mineral loss (%/V) for each group was 4,870 +/- 1,434 (fluoride followed by laser treatment), 6,341 +/- 2,204 (laser treatment), 7,669 +/- 2,255 (fluoride treatment), and 10,779 +/- 2,936 (control). The preventive effect of the laser (p %26lt; 0.001) and fluoride (p = 0.010) treatment was statistically significant. Characterized by micro-x-ray diffraction (XRD) analysis, the significant contraction in the a-axis after both laser and combined laser/fluoride treatment was revealed (both p %26lt; 0.05). In conclusion, subablative low-energy Er:YAG laser irradiation following fluoride treatment may instantaneously transform enamel hydroxyapatite into fluoridated hydroxyapatite to reduce enamel solubility as a preventive treatment for enamel demineralization.

• 出版日期2013-1
• 单位南阳理工学院