Application of liquid chromatography-tandem mass spectrometry in quantitative bioanalyses of organic molecules in aquatic environment and organisms

作者：Bussy Ugo; Li Ke; Li Weiming

来源：Environmental Science and Pollution Research, 2016, 23(10): 9459-9479.

DOI：10.1007/s11356-016-6433-7

• Liquid chromatography-tandem mass spectrometry
• LC-MS/MS
• Sample preparation
• Pharmaceuticals
• Emergent pollutants
• Aquatic organisms
• Environmental water

Analytical methods using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) for the simultaneous determination of metabolites or contaminants (or both) in various tissues of aquatic organisms and in the aquatic environment have received increasing attention in the last few years. This review discusses the findings relevant to such procedures published between 2005 and 2015. The aim is to evaluate the advantages, restrictions, and performances of the procedures from sample preparation to mass spectrometry measurement. To support these discussions, a general knowledge on LC-MS/MS is also provided.

• 出版日期2016-5