Macrophage Supply and Demand at the Core of the Necrotic Granuloma

作者:Randolph Gwendalyn J*
来源:Cell Host & Microbe, 2015, 18(1): 3-4.
DOI:10.1016/j.chom.2015.06.014

摘要

Central necrosis of granulomas is linked to progression of major diseases, including tuberculosis and atherosclerosis. In this issue of Cell Host & Microbe, Pagan et al. (2015) reveal that necrotic granulomas develop when macrophage supply is insufficient. These findings suggest augmenting macrophage availability as a therapeutic strategy in tuberculosis.

  • 出版日期2015-7-8