Anti-inflammatory Diterpenoids from Croton tonkinensis

作者:Kuo Ping Chung; Yang Mei Lin; Hwang Tsong Long; Lai Yuan Yu; Li Yue Chiun; Tran Dinh Thang; Wu Tian Shung*
来源:Journal of Natural Products, 2013, 76(2): 230-236.
DOI:10.1021/np300699f

摘要

Phytochemical investigation of the methanolic extract of Croton tonkinensis afforded two known kauranes (1, 2), eight new ent-kauranes (3-10), and 16 known ent-kaurane-type diterpenoids (12-27). In addition, 30 known compounds were identified by comparison of their physical and spectroscopic data with reported data. Among the isolated compounds, ent-18-acetoxykaur-16-en-15-one (20) displayed the most significant inhibition of superoxide anion generation and elastase release.

  • 出版日期2013-2
  • 单位长春大学