Anti-inflammatory and immunomodulatory properties of Carica papaya

作者:Pandey Saurabh; Cabot Peter J; Shaw P Nicholas; Hewavitharana Amitha K*
来源:Journal of Immunotoxicology, 2016, 13(4): 590-602.
DOI:10.3109/1547691X.2016.1149528

摘要

Chronic inflammation is linked with the generation and progression of various diseases such as cancer, diabetes and atherosclerosis, and anti-inflammatory drugs therefore have the potential to assist in the treatment of these conditions. Carica papaya is a tropical plant that is traditionally used in the treatment of various ailments including inflammatory conditions. A literature search was conducted by using the keywords papaya, anti-inflammatory and inflammation and immunomodulation and immune along with cross-referencing. Both in vitro and in vivo investigation studies were included. This is a review of all studies published since 2000 on the anti-inflammatory activity of papaya extracts and their effects on various immune-inflammatory mediators. Studies on the anti-inflammatory activities of recognized phytochemicals present in papaya are also included. Although in vitro and in vivo studies have shown that papaya extracts and papaya-associated phytochemicals possess anti-inflammatory and immunomodulatory properties, clinical studies are lacking.

  • 出版日期2016-7