科研之友
微信
新浪微博
Facebook
分享链接
摘要
Background. Dyspnea is a prominent symptom in asthma. The Dyspnea-12 (D-12), an instrument that quantifies breathlessness using 12 descriptors that tap the physical and affective aspects, has shown promise for the measurement of dyspnea in cardiorespiratory disease. Objective. We report the results of a study designed to test the validity and reliability of the D-12 in a population of patients with asthma. Methods. This cross-sectional study included 102 patients with asthma. Subjects completed the D-12, Hospital Anxiety and Depression scale, St. George''s Respiratory Questionnaire (SGRQ), and Medical Research Council scale. Confirmatory factor analysis confirmed the two-component structure of the D-12 (i.e., seven items that tap the physical aspects of breathlessness and five items that tap the affective aspects). Results. The D-12 subscales had excellent internal reliability (Cronbach''s alpha for the ""physical"" score was 0.94 and the affective score was 0.95). The D-12 physical component was more strongly correlated with SGRQ Symptoms (r == 0.648), SGRQ Activities (r == 0.635) and Medical Research Council grade (r == 0.636), while the affective component was more strongly correlated with SGRQ Impacts (r == 0.765) and Hospital Anxiety and Depression scale scores (anxiety r == 0.641 and depression r == 0.602). Conclusion. This study supports validity of the D-12 for use in the assessment of dyspnea of patients with asthma. It assesses one of the most pertinent symptoms of asthma from two viewpoints--physical and affective.</.
- 出版日期2011-8
