A novel dual energy method for enhanced quantitative computed tomography

作者：Emami A; Ghadiri H^*; Rahmim A; Ay R

来源：Journal of Instrumentation, 2018, 13(01): P01030.

DOI：10.1088/1748-0221/13/01/P01030

• Computerized Tomography (CT) and Computed Radiography (CR)
• Software architectures (event data models frameworks and databases)

Accurate assessment of bone mineral density (BMD) is critically important in clinical practice, and conveniently enabled via quantitative computed tomography (QCT). Meanwhile, dual-energy QCT (DEQCT) enables enhanced detection of small changes in BMD relative to single-energy QCT (SEQCT). In the present study, we aimed to investigate the accuracy of QCT methods, with particular emphasis on a new dual-energy approach, in comparison to single-energy and conventional dual-energy techniques. We used a sinogram-based analytical CT simulator to model the complete chain of CT data acquisitions, and assessed performance of SEQCT and different DEQCT techniques in quantification of BMD. We demonstrate a 120% reduction in error when using a proposed dual-energy Simultaneous Equation by Constrained Least-squares method, enabling more accurate bone mineral measurements.

• 出版日期2018-1