Antimicrobial activities of diterpene labdane from seeds of Byrsonima crassifolia

作者：Muniz Ramirez Alethia; Martha Perez Gutierrez Rosa; Garcia Baez Efren; Maria Mota Flores Jose

来源：Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, 2014, 13(1): 31-37.

• Byrsonima crassifolia
• diterpene
• labdane
• antimicrobial

Two compounds from the hexane extract of seeds of Byrsonima crassifolia were isolated and their structures elucidated using extensive spectroscopic analyses. These compounds are derived from the new labdane diterpene Labda-17-(1) and the known antimicrobial Labda-8 (17)-(2). The present study was aimed to study the effect antimicrobial of novel diterpene 1 against bacterial pathogens showed a moderate activity with MIC values 18.79-70.12 mu g/ml and a MBC ranging between 250-1000 mu g/ml against all assayed microorganisms.

• 出版日期2014-1