Neurogenic stunned myocardium after acute hydrocephalus Report of 2 cases

作者：Johnson Jeremiah^*; Ragheb John; Garg Ruchira; Patten William; Sandberg David I; Bhatia Sanjiv

来源：Journal of Neurosurgery-Pediatrics, 2010, 5(5): 428-433.

DOI：10.3171/2009.11.PEDS09341

• herniation
• hydrocephalus
• takotsubo cardiomyopathy
• neurogenic stunned myocardium

Neurogenic stunned myocardium (NSM) is a syndrome of cardiac stunning after a neurological insult. It is commonly observed after aneurysmal subarachnoid hemorrhage but is increasingly being reported after other neurological events. The underlying mechanism of NSM is believed to be a hypothalamic-mediated sympathetic surge causing weakened cardiac contractility and even direct cardiac myocyte damage. The authors report 2 cases of NSM in pediatric patients after acute hydrocephalus. Both patients experienced severe cardiac dysfunction in the acute phase but ultimately had a good neurological outcome and a full cardiac recovery. The identification, treatment, and outcome in 2 rare pediatric cases of NSM are discussed, and the history of the brain-cardiac connection is reviewed. (DOI: 10.3171/2009.11.PEDS09341)

• 出版日期2010-5