A Therapy for Liver Failure Found in the JNK Yard

作者:Willenbring Holger*; Grompe Markus
来源:Cell, 2013, 153(2): 283-284.
DOI:10.1016/j.cell.2013.03.033

摘要

In the liver, the hepatocyte mass is kept stable through a tight balance between hepatocyte death and proliferation that is frequently lost upon acute or chronic liver injury. Wuestefeld et al. (2013) now identify a potentially druggable target that enhances hepatocyte proliferation and promotes liver regeneration, thereby preventing liver failure.

  • 出版日期2013-4-11