Antibiotic Resistance: Development in Surgical Intensive Care

作者：Weiss G^*; Tammer I; Wolff S

来源：Zentralblatt fur Chirurgie, 2011, 136(2): 143-151.

DOI：10.1055/s-0030-1262609

• antibiotic treatment
• antibiotic resistance
• intensive medicine
• risk management
• mechanisms

Background: During the last years we have always found an increase of antibiotic resistance. This increase is combined with high antibiotic consumption. The reasons for the problems are mistakes in the prescription of antibiotics and the increase of risk-patients because of demographic aging and the development and progress of surgery and medicine.
Material and Method: We describe the general development of bacterial resistance and factors that influence it. Data from two intensive care units are evaluated. We describe the main antibiotic-resistant isolates for surgery and the mechanisms to avoid the development of bacterial resistance.
Results: The emergency increase of bacterial resistance shows severe clinical and economical problems. For surgery especially the multidrug-resistant Gram-negative organisms represent an important hygienic and therapeutic problem.
Conclusion: In order to positively influence the development of bacterial resistance, strict guidelines, especially for intensive stations, must be consequently applied and controlled. In spite of knowledge of these problems for a number of years many reserves are still available for the care of critical patients.

• 出版日期2011-4