Aluminium Nitrate Nonahydrate (Al(NO3)3 center dot 9 H2O): An Efficient Oxidant Catalyst for the One-Pot Synthesis of Biginelli Compounds from Benzyl Alcohols

作者：Kolvari Eskandar^*; Zolfigol Mohammad Ali; Mirzaeean Maryam

来源：Helvetica Chimica Acta, 2012, 95(1): 115-119.

DOI：10.1002/hlca.201100242

• Biginelli reaction
• Cyclocondensation
• oxidative
• Pyrimidin-2(1H)-ones
• 3
• 4-dihydro-
• Pyrimidin-2(1H)-thiones
• 3
• 4-dihydro-
• Multicomponent reactions
• Catalysis

A clean and efficient tandem oxidative cyclocondensation process is reported for the synthesis of 3,4-dihydropyrimidin-2(1H)-one or -thione derivatives from primary aryl alcohols, beta-keto esters, and urea or thiourea in the presence of Al(NO3)(3) center dot 9 H2O as oxidant catalyst (Scheme, Table 5).

• 出版日期2012-1