Evaluation of Dry Eye and Meibomian Gland Dysfunction After Cataract Surgery

作者：Han Kyung Eun; Yoon Sang Chul; Ahn Ji Min; Nam Sang Min; Stulting R Doyle; Kim Eung Kweon; Seo Kyoung Yul^*

来源：American Journal of Ophthalmology, 2014, 157(6): 1144-1150.

DOI：10.1016/j.ajo.2014.02.036

PURPOSE: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. %26lt;br%26gt;DESIGN: Prospective observational case series. %26lt;br%26gt;METHODS: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. %26lt;br%26gt;RESULTS: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P %26lt; 0.001 and P %26lt; 0.001, respectively). Lid margin abnormalities were significantly increased (P %26lt; 0.001 and P %26lt; 0.001, respectively) and TBUT decreased postoperatively (P %26lt; 0.001 and P %26lt; 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values %26gt; 0.05). %26lt;br%26gt;CONCLUSION: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.

• 出版日期2014-6