Stereoselective Synthesis of Dienes from N-Allylhydrazones

作者:Mundal Devon A; Lutz Kelly E; Thomson Regan J*
来源:Organic Letters, 2009, 11(2): 465-468.
DOI:10.1021/ol802585r

摘要

A new method for the stereoselective synthesis of dienes from aldehydes and N-allylhydrazine derivatives has been developed. High levels of (E)-stereoselectivity are obtained for a variety of substrates. Addition of a dienophile to the reaction mixture allows a one-flask diene synthesis-cycloaddition sequence.