科研之友
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摘要
We designed and synthesized a Cu-coordination complex based on a seven-membered amide cycle and studied its binding ability with nucleotides (cytidine 5'-monophosphate (CMP), cytidine 5'-diphosphate (CDP), cytidine 5'-triphosphate (CTP), cytidine d-5'-monophosphate (dCMP), and thymidine d-5'-monophosphate (dTMP)) by UV-Vis spectroscopy. Results indicate that the compound shows the highest binding ability with CDP among the studied nucleotides and can selectively and strongly bind nucleotides in neutral aqueous solution. The compound can be used as optical receptor for the detection of CDP.
