Advances in Hematopoietic Stem Cell Transplantation in Chronic Myeloid Leukemia

作者:Veldman Rachel; El Rassi Fuad; Holloway Stacie; Langston Amelia; Khoury Hanna Jean*
来源:Discovery Medicine, 2013, 88: 179-186.

摘要

Treatment of chronic myeloid leukemia (CML) has evolved dramatically with the development of tyrosine kinase inhibitors (TKIs). This past decade also witnessed major advances in the field of allogeneic hematopoietic stem cell transplantation (alloHSCT) that led to better patients' outcomes. Progress in the exploitation of alternative sources of stem cells, development of novel conditioning regimens, discovery of innovative graft-versus-host prophylactic strategies, and advances in supportive care as well as positioning of alloHSCT in the overall management of CML are discussed in this article.

  • 出版日期2013-10