A waitlist-controlled trial of group cognitive behavioural therapy for depression and anxiety in Parkinson%26apos;s disease

作者：Troeung Lakkhina^*; Egan Sarah J; Gasson Natalie

来源：BMC Psychiatry, 2014, 14(1): 19.

DOI：10.1186/1471-244X-14-19

• Depression
• Anxiety
• Parkinson%26apos
• s disease
• Cognitive behavioural therapy
• Psychotherapy
• Treatment
• Randomised controlled trial

Background: The aim of this study was to evaluate the efficacy of a group Cognitive Behavioural Therapy (CBT) treatment for depression and anxiety in Parkinson%26apos;s disease (PD). %26lt;br%26gt;Methods: A waitlist-controlled trial design was used. Eighteen adults with PD and a comorbid DSM-IV-TR diagnosis of depression and/or anxiety were randomised to either Intervention (8-week group CBT treatment) or Waitlist (8-week clinical monitoring preceding treatment). The Depression, Anxiety, Stress Scale-21 (DASS-21) was the primary outcome. Assessments were completed at Time 1 (pretreatment), Time 2 (posttreatment/post-waitlist) and 1-month and 6-month follow-ups. %26lt;br%26gt;Results: At Time 2, participants who received CBT reported greater reductions in depression (Mchange = -2.45) than Waitlist participants (Mchange =.29) and this effect was large, d = 1.12, p =.011. Large secondary effects on anxiety were also observed for CBT participants, d =.89, p = .025. All treatment gains were maintained and continued to improve during the follow-up period. At 6-month follow-up, significant and large effects were observed for both depression (d = 2.07) and anxiety (d = 2.26). %26lt;br%26gt;Conclusions: Group CBT appears to be an efficacious treatment approach for depression and anxiety in PD however further controlled trials with larger numbers of participants are required.

• 出版日期2014-1-27