A facile synthesis of sugar-pyrazole derivatives

作者：Hemamalini Arasappan; Nagarajan Subbiah; Das Thangamuthu Mohan^*

来源：Carbohydrate Research, 2011, 346(13): 1814-1819.

DOI：10.1016/j.carres.2011.06.019

• Pyrazole
• alpha,beta-Unsaturated ketones
• Self-oxidation
• Knoevenagel condensation
• Sugar-heterocyclics
• C-beta-Glycosides

A facile synthesis of sugar-pyrazole derivatives has been accomplished by condensation of sugar-chalcone with hydrazine hydrate under neutral conditions resulting in yields of 70-85%. The products are characterized by FTIR and NMR spectroscopy and by elemental analysis. The beta-anomeric forms for these derivatives were assigned by NMR spectroscopy.

• 出版日期2011-9-27