A Case Study of Thiourea-Assisted Iminium Formation by Hydroxyl Anion Binding: Kinetic, Spectroscopic and Computational Evidences

作者：Juste Navarro Veronica; Prieto Liher; Delso Ignacio; Manzano Ruben; Tejero Tomas; Reyes Efraim; Vicario Jose L; Merino Pedro

来源：Advanced Synthesis & Catalysis, 2017, 359(23): 4122-4128.

DOI：10.1002/adsc.201700986

• Thioureas
• Iminium catalysis
• Nitrones
• Hydroxide binding
• Squaramides

Abstract(#br)The experimental and computational study of the mechanism of the iminium‐organocatalyzed formation of N ‐hydroxypyrrolidines from nitrones, revealed up to three activation levels of the Schreiner's thiourea used as co‐catalyst, i.e: (i) formation of the iminium ion through hydroxyl anio...

• 出版日期2017-12-11