UTILITY OF PROTEIN ELECTROPHORETIC ANALYSIS IN THE CHARACTERIZATION OF MALIGNANT-TISSUES

作者:UNTEREGGER G*
来源:Journal of Chromatography - Biomedical Applications, 1991, 569(1-2): 367-388.
DOI:10.1016/0378-4347(91)80238-8

摘要

High-resolution electrophoresis of samples from malignant tissues and tumour cells has developed from a simple analytical tool to a high-tech system requiring a lot of satellite techniques. Though this developmental history now demands additional expensive instrumentation and a detailed knowledge of protein chemistry, the usefulness of this technique in tumour biology has been dramatically enhanced. Consequently, electrophoretic techniques combined with additional high-resolution and sensitive analytical tools can now be used to elucidate a particular phenotype of a cancer cell; moreover, the chemical nature of this phenotype can be revealed. The way from the protein backwards to the gene is now open!

  • 出版日期1991-9-13